P04 - ILLUMINATE-C, a Single-arm, Phase 3 Study of Lumasiran in Patients with Primary Hyperoxaluria Type 1 and CKD3b-5, Including Those on Hemodialysis

Understand and recall that lumasiran, an RNAi therapeutic indicated for the treatment of
primary hyperoxaluria type 1 (PH1) to lower urinary oxalate levels in children and adults, can substantially reduce plasma oxalate in patients with PH1 and CKD 3b–5, with an acceptable safety profile through 6-months of treatment.